WebAnti-TROP2 Antibody, clone TrMab-29 Anti-TROP2, clone TrMab-29, Cat. No. MABS2310, is a mouse monoclonal antibody that detects TROP2 and is tested for use in Flow Cytometry, Immunohistochemistry, and Western Blotting. ... Cell surface glycoprotein Trop-2; ... which is subsequently cleaved off to generate the mature form that contains an ... WebAntibodies that detect TROP2 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target TROP2 in Human, Mouse and Rat samples. Our TROP2 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and …
NOTCH2 (Cleaved Ala1734) Polyclonal Antibody - Thermo Fisher Scientific
WebTrop-2 is a transmembrane glycoprotein (E. Guerra et al., The Trop-2 signalling network in cancer growth. Oncogene 32, 1594- 1600 (2013)), that is cleaved and activated by ADAM10 to induce cancer growth and metastatic dif- fusion (M. Trerotola et al., Trop-2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis. WebAnti-TROP2, clone TrMab-29, Cat. No. MABS2310, is a mouse monoclonal antibody that detects TROP2 and is tested for use in Flow Cytometry, Immunohistochemistry, and Western Blotting. New MABS2310-100UG 100 μg Price could not be retrieved Recommended Products Overview Supporting Documentation Related Products & … cheesecake factory gift cards online
Datopotamab Deruxtecan, a Novel TROP2-directed …
WebFeb 13, 2024 · Most breast cancers have cells that express the protein Trop-2. Sacituzumab govitecan (Trodelvy) is a Trop-2 antibody-drug conjugate. It combines a Trop-2 antibody and the chemotherapy drug SN-38. This combination allows the targeted delivery of SN-38 to cancer cells that express Trop-2. WebFeb 1, 2024 · 3.2. Antibody-drug conjugates targeting Trop-2. Trophoblast cell surface antigen 2 is a transmembrane glycoprotein. It is encoded by the tumor-associated calcium signal transducer 2 (TACSTD2) gene located on the chromosomal region 1p32, and represents an emerging target for the treatment of solid tumors. It acts as a calcium … WebApr 8, 2024 · Trop-2 is a transmembrane signal transducer that can induce cancer growth. Using antibody targeting and N-terminal Edman degradation, we show here that Trop-2 undergoes cleavage in the first thyroglobulin domain loop of its extracellular region, between residues R87 and T88. cheesecake factory gift cards walgreens