WebMay 4, 2024 · Genome-wide polygenic score to predict chronic kidney disease across ancestries; Improving polygenic prediction in ancestrally diverse populations; Mapping genomic loci implicates genes and synaptic biology in schizophrenia; Cross-ethnicity/race generalization failure of behavioral prediction from resting-state functional connectivity WebApr 8, 2024 · Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Mapping genomic loci implicates genes and synaptic biology in …
Mapping genomic loci implicates genes …
WebDec 10, 2024 · For example, visualizing GWAS loci across ∼100 complex traits for the major histocompatibility complex (MHC) region—the single most pleiotropic region in the human genome that harbors long-range linkage disequilibrium (LD)—requires plotting 66 000 single-nucleotide polymorphisms (SNPs) × 120 traits ≈ 8 million data points with ... WebHere, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the central nervous system, but not in other ... can drinking diet soda cause cancer
Landmark study implicates specific genes in schizophrenia
WebApr 6, 2024 · Dec. 23, 2024 — Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated … WebAug 14, 2024 · Genome-wide polygenic score to predict chronic kidney disease across ancestries; Improving polygenic prediction in ancestrally diverse populations; Mapping genomic loci implicates genes and synaptic biology in schizophrenia; Cross-ethnicity/race generalization failure of behavioral prediction from resting-state functional connectivity WebIntrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disorder affecting 0.5–2% of pregnancies. The majority of cases present in the third trimester with pruritus, elevated serum bile acids and abnormal serum liver tests. ICP is fishtail neon chicago